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T*
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[(The)-310.9(software)-311.4(package)-317.6(GROMACS)-312.7(5.1.2)-315.4(was)-310.4(used)-310.6(for)-314.3(all)]TJ
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T*
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7.3823 0 0 6.5614 546.2361 630.8219 Tm
(3)Tj
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[(\(Fortes,)-288.5(2000\).)-291.1(Each)-290.1(systems)-292.9(energy)-291.1(was)-293.1(minimized)-291.6(by)-290.2(us-)]TJ
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[(ing)-527.6(steepest)-536.3(descent)-535.3(for)-533.1(1000)-528.5(steps.)-534(To)-533.3(allow)-531.9(for)-533.1(some)]TJ
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T*
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T*
[(restrained)-435(simulations,)-438.5(the)-430.8(temperature)-438.7(of)-434.1(the)-436.6(system)-435(was)]TJ
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ET
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59.754 114.123 l
W n
q
490.48 0 0 397.19 59.754 114.123 cm
/Im1 Do
Q
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BT
/F7 1 Tf
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[(FIG.)-238.8(1.)]TJ
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T*
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/F4 1 Tf
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[(PROTEIN)-336.1(STABILITY)-341.6(IN)-335.1(TITANS)-331.7(SUBSURFACE)-338.7(OCEAN)-27406.6(3)]TJ
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